The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis

The Rev1-Polζ pathway is believed to be the major mechanism of translesion DNA synthesis and base damage-induced mutagenesis in eukaryotes. While it is widely believed that Rev1 plays a non-catalytic function in translesion synthesis, the role of its dCMP transferase activity remains uncertain. To d...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Wang, Jillian, Zhang, Yanbin, Wang, Zhigang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926598/
https://www.ncbi.nlm.nih.gov/pubmed/20388628
http://dx.doi.org/10.1093/nar/gkq225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926598/
https://www.ncbi.nlm.nih.gov/pubmed/20388628
http://dx.doi.org/10.1093/nar/gkq225

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