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A bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helix
Direct targeting of critical DNA-binding elements of a repressor by its cognate antirepressor is an effective means to sequester the repressor and remove a transcription initiation block. Structural descriptions for this, though often proposed for bacterial and phage repressor–antirepressor systems,...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926617/ https://www.ncbi.nlm.nih.gov/pubmed/20410074 http://dx.doi.org/10.1093/nar/gkq277 |