Cargando…

Sequence-specific recognition of methylated DNA by human zinc-finger proteins

DNA methylation is an essential epigenetic mark. Three classes of mammalian proteins recognize methylated DNA: MBD proteins, SRA proteins and the zinc-finger proteins Kaiso, ZBTB4 and ZBTB38. The last three proteins can bind either methylated DNA or unmethylated consensus sequences; how this is achi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sasai, Nobuhiro, Nakao, Mitsuyoshi, Defossez, Pierre-Antoine
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926618/ https://www.ncbi.nlm.nih.gov/pubmed/20403812 http://dx.doi.org/10.1093/nar/gkq280

Ejemplares similares

On the dependent recognition of some long zinc finger proteins
por: Zuo, Zheng, et al.
Publicado: (2023)

The zinc fingers of YY1 bind single-stranded RNA with low sequence specificity
por: Wai, Dorothy C.C., et al.
Publicado: (2016)

Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
por: Lam, Kathy N., et al.
Publicado: (2011)

Structures of CTCF–DNA complexes including all 11 zinc fingers
por: Yang, Jie, et al.
Publicado: (2023)

Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor
por: Burdach, Jon, et al.
Publicado: (2014)

MIR sequences recruit zinc finger protein ZNF768 to expressed genes
por: Rohrmoser, Michaela, et al.
Publicado: (2019)

Deciphering the DNA code for the function of the Drosophila polydactyl zinc finger protein Suppressor of Hairy-wing
por: Baxley, Ryan M., et al.
Publicado: (2017)

Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain
por: Lim, Wooi F., et al.
Publicado: (2016)

Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability
por: Gillinder, Kevin R., et al.
Publicado: (2017)

The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances
por: Monteagudo-Sánchez, Ana, et al.
Publicado: (2020)

A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation
por: Yakhou, Lounis, et al.
Publicado: (2023)

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells
por: Miotto, Benoit, et al.
Publicado: (2018)

Role for first zinc finger of WT1 in DNA sequence specificity: Denys–Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites
por: Wang, Dongxue, et al.
Publicado: (2018)

Structural basis for Klf4 recognition of methylated DNA
por: Liu, Yiwei, et al.
Publicado: (2014)

Dissecting the function of the adult β-globin downstream promoter region using an artificial zinc finger DNA-binding domain
por: Barrow, Joeva J., et al.
Publicado: (2014)

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property
por: Cogoi, Susanna, et al.
Publicado: (2014)

Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta
por: Hong, Samuel, et al.
Publicado: (2017)

Sequence-specific dynamics of DNA response elements and their flanking sites regulate the recognition by AP-1 transcription factors
por: Hörberg, Johanna, et al.
Publicado: (2021)

Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary
por: Soshnev, Alexey A., et al.
Publicado: (2012)

Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation
por: Kwak, Sojung, et al.
Publicado: (2018)

Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors
por: Naciri, Ikrame, et al.
Publicado: (2019)

Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA
por: Clouaire, Thomas, et al.
Publicado: (2010)

The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription
por: Yang, Yisheng, et al.
Publicado: (2009)

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2
por: Guo, Yahong, et al.
Publicado: (2009)

The interplay between DNA methylation and sequence divergence in recent human evolution
por: Hernando-Herraez, Irene, et al.
Publicado: (2015)

The Igf2/H19 imprinting control region exhibits sequence-specific and cell-type-dependent DNA methylation-mediated repression
por: Chen, Yinming, et al.
Publicado: (2009)

Flanking sequence preference modulates de novo DNA methylation in the mouse genome
por: Mallona, Izaskun, et al.
Publicado: (2020)

PRR5, 7 and 9 positively modulate TOR signaling-mediated root cell proliferation by repressing TANDEM ZINC FINGER 1 in Arabidopsis
por: Li, Bin, et al.
Publicado: (2019)

Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A
por: Kelly, Richard D. W., et al.
Publicado: (2012)

A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
por: Roh, Hyun Cheol, et al.
Publicado: (2015)

Decoupling of divergent gene regulation by sequence-specific DNA binding factors
por: Yan, Chao, et al.
Publicado: (2015)

Identification of DNA motifs that regulate DNA methylation
por: Wang, Mengchi, et al.
Publicado: (2019)

MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis
por: Santolini, Marc, et al.
Publicado: (2016)

Genome-wide evidence for local DNA methylation spreading from small RNA-targeted sequences in Arabidopsis
por: Ahmed, Ikhlak, et al.
Publicado: (2011)

Distinctive sequence patterns in metazoan and yeast nucleosomes: Implications for linker histone binding to AT-rich and methylated DNA
por: Cui, Feng, et al.
Publicado: (2009)

Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation
por: Khamis, Hadeel, et al.
Publicado: (2021)

Single-molecule mitochondrial DNA sequencing shows no evidence of CpG methylation in human cells and tissues
por: Bicci, Iacopo, et al.
Publicado: (2021)

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition
por: Furukawa, Takanori, et al.
Publicado: (2020)

MCAF1 and synergistic activation of the transcription of Epstein–Barr virus lytic genes by Rta and Zta
por: Chang, Li-Kwan, et al.
Publicado: (2010)

Ligand-dependent corepressor contributes to transcriptional repression by C(2)H(2) zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1
por: Calderon, Mario R., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_j32ts86kcc6qsc78qla62m07tl