The role of prophylactic anticonvulsants in moderate to severe head injury

BACKGROUND: Post-traumatic seizures cause secondary brain injury, contributing to morbidity and mortality after traumatic brain injury. Seizure activity may be undetectable if the patient is paralysed and ventilated. AIMS: The effect of prophylactic anticonvulsant therapy on the prevention of seizur...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Arshad Ali, Banerjee, Ashis
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926870/
https://www.ncbi.nlm.nih.gov/pubmed/21031044
http://dx.doi.org/10.1007/s12245-010-0180-1
Descripción
Sumario:BACKGROUND: Post-traumatic seizures cause secondary brain injury, contributing to morbidity and mortality after traumatic brain injury. Seizure activity may be undetectable if the patient is paralysed and ventilated. AIMS: The effect of prophylactic anticonvulsant therapy on the prevention of seizures after moderate to severe traumatic brain injury was studied. METHODS: A structured systematic literature review was performed. RESULTS: There may be a place for prophylactic anticonvulsants in the prophylaxis of early post-traumatic seizures. CONCLUSION: Further randomised controlled trials are needed to firmly establish the benefits of prophylactic anticonvulsants.

Ejemplares similares