Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population

PURPOSE: Neurotrophin-4 protein (NT-4) plays a role in the protection of retinal ganglion cells by activating tyrosine kinase B (TrkB) receptors. A recent study identified mutations within the neurotrophin-4 (NTF4) gene to account for 1.7% of primary open-angle glaucoma (POAG) in Europeans. The aim...

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Detalles Bibliográficos
Autores principales: Vithana, Eranga N., Nongpiur, Monisha E., Venkataraman, Divya, Chan, Stephanie H., Mavinahalli, Jagadeesh, Aung, Tin
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927376/
https://www.ncbi.nlm.nih.gov/pubmed/20806036

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