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RNA Interference inhibits Hepatitis B Virus of different genotypes in Vitro and in Vivo

BACKGROUND: Hepatitis B virus (HBV) infection increases the risk of liver disease and hepatocellular carcinoma. Small interfering RNA (siRNA) can be a potential new tool for HBV therapy. Given the high heterogeneity of HBV strains and the sensitivity towards sequences changes of siRNA, finding a pot...

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Detalles Bibliográficos
Autores principales: Zhang, Ya-Li, Cheng, Tong, Cai, Yi-Jun, Yuan, Quan, Liu, Che, Zhang, Tao, Xia, De-Zhen, Li, Rui-Yin, Yang, Lian-Wei, Wang, Ying-Bin, Yeo, Anthony ET, Shih, James Wai-Kuo, Zhang, Jun, Xia, Ning-shao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927532/
https://www.ncbi.nlm.nih.gov/pubmed/20696079
http://dx.doi.org/10.1186/1471-2180-10-214