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Distinguishing between cancer driver and passenger gene alteration candidates via cross-species comparison: a pilot study
BACKGROUND: We are developing a cross-species comparison strategy to distinguish between cancer driver- and passenger gene alteration candidates, by utilizing the difference in genomic location of orthologous genes between the human and other mammals. As an initial test of this strategy, we conducte...
Autores principales: | Ji, Xinglai, Tang, Jie, Halberg, Richard, Busam, Dana, Ferriera, Steve, Peña, Maria Marjorette O, Venkataramu, Chinnambally, Yeatman, Timothy J, Zhao, Shaying |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927548/ https://www.ncbi.nlm.nih.gov/pubmed/20707908 http://dx.doi.org/10.1186/1471-2407-10-426 |
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