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Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

OBJECTIVE: Type 2 diabetes and insulin resistance have been associated with mitochondrial dysfunction, but it is debated whether this is a primary factor in the pathogenesis of the disease. To test the concept that mitochondrial dysfunction is secondary to the development of insulin resistance, we e...

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Detalles Bibliográficos
Autores principales:	Hoeks, Joris, van Herpen, Noud A., Mensink, Marco, Moonen-Kornips, Esther, van Beurden, Denis, Hesselink, Matthijs K.C., Schrauwen, Patrick
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927932/ https://www.ncbi.nlm.nih.gov/pubmed/20573749 http://dx.doi.org/10.2337/db10-0519

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