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A Novel Clinically Relevant Strategy to Abrogate Autoimmunity and Regulate Alloimmunity in NOD Mice

OBJECTIVE: To investigate a new clinically relevant immunoregulatory strategy based on treatment with murine Thymoglobulin mATG Genzyme and CTLA4-Ig in NOD mice to prevent allo- and autoimmune activation using a stringent model of islet transplantation and diabetes reversal. RESEARCH DESIGN AND METH...

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Detalles Bibliográficos
Autores principales:	Vergani, Andrea, D'Addio, Francesca, Jurewicz, Mollie, Petrelli, Alessandra, Watanabe, Toshihiko, Liu, Kaifeng, Law, Kenneth, Schuetz, Christian, Carvello, Michele, Orsenigo, Elena, Deng, Shaoping, Rodig, Scott J., Ansari, Javeed M., Staudacher, Carlo, Abdi, Reza, Williams, John, Markmann, James, Atkinson, Mark, Sayegh, Mohamed H., Fiorina, Paolo
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927948/ https://www.ncbi.nlm.nih.gov/pubmed/20805386 http://dx.doi.org/10.2337/db09-1264

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