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Müller Cell-Derived VEGF Is Essential for Diabetes-Induced Retinal Inflammation and Vascular Leakage

OBJECTIVE: Vascular endothelial growth factor (VEGF-A or VEGF) is a major pathogenic factor and therapeutic target for diabetic retinopathy (DR). Since VEGF has been proposed as a survival factor for retinal neurons, defining the cellular origin of pathogenic VEGF is necessary for the effectiveness...

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Detalles Bibliográficos
Autores principales: Wang, Juanjuan, Xu, Xueliang, Elliott, Michael H., Zhu, Meili, Le, Yun-Zheng
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927953/
https://www.ncbi.nlm.nih.gov/pubmed/20530741
http://dx.doi.org/10.2337/db09-1420