Mass spectrometry–based proteomics in cell biology

The global analysis of protein composition, modifications, and dynamics are important goals in cell biology. Mass spectrometry (MS)–based proteomics has matured into an attractive technology for this purpose. Particularly, high resolution MS methods have been extremely successful for quantitative an...

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Detalles Bibliográficos
Autores principales: Walther, Tobias C., Mann, Matthias
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928005/
https://www.ncbi.nlm.nih.gov/pubmed/20733050
http://dx.doi.org/10.1083/jcb.201004052
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author Walther, Tobias C.
Mann, Matthias
author_facet Walther, Tobias C.
Mann, Matthias
author_sort Walther, Tobias C.
collection PubMed
description The global analysis of protein composition, modifications, and dynamics are important goals in cell biology. Mass spectrometry (MS)–based proteomics has matured into an attractive technology for this purpose. Particularly, high resolution MS methods have been extremely successful for quantitative analysis of cellular and organellar proteomes. Rapid advances in all areas of the proteomic workflow, including sample preparation, MS, and computational analysis, should make the technology more easily available to a broad community and turn it into a staple methodology for cell biologists.
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spelling pubmed-29280052011-02-23 Mass spectrometry–based proteomics in cell biology Walther, Tobias C. Mann, Matthias J Cell Biol Reviews The global analysis of protein composition, modifications, and dynamics are important goals in cell biology. Mass spectrometry (MS)–based proteomics has matured into an attractive technology for this purpose. Particularly, high resolution MS methods have been extremely successful for quantitative analysis of cellular and organellar proteomes. Rapid advances in all areas of the proteomic workflow, including sample preparation, MS, and computational analysis, should make the technology more easily available to a broad community and turn it into a staple methodology for cell biologists. The Rockefeller University Press 2010-08-23 /pmc/articles/PMC2928005/ /pubmed/20733050 http://dx.doi.org/10.1083/jcb.201004052 Text en © 2010 Walther and Mann This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Walther, Tobias C.
Mann, Matthias
Mass spectrometry–based proteomics in cell biology
title Mass spectrometry–based proteomics in cell biology
title_full Mass spectrometry–based proteomics in cell biology
title_fullStr Mass spectrometry–based proteomics in cell biology
title_full_unstemmed Mass spectrometry–based proteomics in cell biology
title_short Mass spectrometry–based proteomics in cell biology
title_sort mass spectrometry–based proteomics in cell biology
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928005/
https://www.ncbi.nlm.nih.gov/pubmed/20733050
http://dx.doi.org/10.1083/jcb.201004052
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