Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

Tissue stiffening is a hallmark of fibrotic disorders but has traditionally been regarded as an outcome of fibrosis, not a contributing factor to pathogenesis. In this study, we show that fibrosis induced by bleomycin injury in the murine lung locally increases median tissue stiffness sixfold relati...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Mih, Justin D., Shea, Barry S., Kho, Alvin T., Sharif, Asma S., Tager, Andrew M., Tschumperlin, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928007/
https://www.ncbi.nlm.nih.gov/pubmed/20733059
http://dx.doi.org/10.1083/jcb.201004082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928007/
https://www.ncbi.nlm.nih.gov/pubmed/20733059
http://dx.doi.org/10.1083/jcb.201004082

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