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Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting
The signal recognition particle (SRP) and SRP receptor comprise the major cellular machinery that mediates the cotranslational targeting of proteins to cellular membranes. It remains unclear how the delivery of cargos to the target membrane is spatially coordinated. We show here that phospholipid bi...
Autores principales: | Lam, Vinh Q., Akopian, David, Rome, Michael, Henningsen, Doug, Shan, Shu-ou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928010/ https://www.ncbi.nlm.nih.gov/pubmed/20733058 http://dx.doi.org/10.1083/jcb.201004129 |
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