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How cyclin A destruction escapes the spindle assembly checkpoint

The anaphase-promoting complex/cyclosome (APC/C) is the ubiquitin ligase essential to mitosis, which ensures that specific proteins are degraded at specific times to control the order of mitotic events. The APC/C coactivator, Cdc20, is targeted by the spindle assembly checkpoint (SAC) to restrict AP...

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Detalles Bibliográficos
Autores principales:	Di Fiore, Barbara, Pines, Jonathon
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928024/ https://www.ncbi.nlm.nih.gov/pubmed/20733051 http://dx.doi.org/10.1083/jcb.201001083

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