HDM2 ERKs PCNA

In this issue, a study by Groehler and Lannigan (2010. J. Cell Biol. doi:10.1083/jcb.201002124) sheds light on the regulation of proliferating cell nuclear antigen (PCNA) turnover and how it is counteracted by the small chromatin-bound kinase ERK8 (extracellular signal-regulated kinase 8). Important...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai Dang, Bielinsky, Anja-Katrin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928025/
https://www.ncbi.nlm.nih.gov/pubmed/20733049
http://dx.doi.org/10.1083/jcb.201007096
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author Nguyen, Hai Dang
Bielinsky, Anja-Katrin
author_facet Nguyen, Hai Dang
Bielinsky, Anja-Katrin
author_sort Nguyen, Hai Dang
collection PubMed
description In this issue, a study by Groehler and Lannigan (2010. J. Cell Biol. doi:10.1083/jcb.201002124) sheds light on the regulation of proliferating cell nuclear antigen (PCNA) turnover and how it is counteracted by the small chromatin-bound kinase ERK8 (extracellular signal-regulated kinase 8). Importantly, inactivation of ERK8 results in genome instability and is associated with cell transformation.
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spelling pubmed-29280252011-02-23 HDM2 ERKs PCNA Nguyen, Hai Dang Bielinsky, Anja-Katrin J Cell Biol Reviews In this issue, a study by Groehler and Lannigan (2010. J. Cell Biol. doi:10.1083/jcb.201002124) sheds light on the regulation of proliferating cell nuclear antigen (PCNA) turnover and how it is counteracted by the small chromatin-bound kinase ERK8 (extracellular signal-regulated kinase 8). Importantly, inactivation of ERK8 results in genome instability and is associated with cell transformation. The Rockefeller University Press 2010-08-23 /pmc/articles/PMC2928025/ /pubmed/20733049 http://dx.doi.org/10.1083/jcb.201007096 Text en © 2010 Nguyen and Bielinsky This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Nguyen, Hai Dang
Bielinsky, Anja-Katrin
HDM2 ERKs PCNA
title HDM2 ERKs PCNA
title_full HDM2 ERKs PCNA
title_fullStr HDM2 ERKs PCNA
title_full_unstemmed HDM2 ERKs PCNA
title_short HDM2 ERKs PCNA
title_sort hdm2 erks pcna
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928025/
https://www.ncbi.nlm.nih.gov/pubmed/20733049
http://dx.doi.org/10.1083/jcb.201007096
work_keys_str_mv AT nguyenhaidang hdm2erkspcna
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