Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI

BACKGROUND: Cooperation of constituents of the ubiquitin proteasome system (UPS) with chaperone proteins in degrading proteins mediate a wide range of cellular processes, such as synaptic function and neurotransmission, gene transcription, protein trafficking, mitochondrial function and metabolism,...

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Detalles Bibliográficos
Autores principales: Li, Xing'an, Zhang, Yingjiu, Xie, Peng, Piao, Jinhua, Hu, Yihong, Chang, Ming, Liu, Tao, Hu, Linsen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928238/
https://www.ncbi.nlm.nih.gov/pubmed/20704702
http://dx.doi.org/10.1186/1471-2202-11-95

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