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Cyclosporine-A therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas: a case report

INTRODUCTION: Breast adenoma is common. However, in the setting of post-transplantation immune suppression it may be expressed differently. CASE PRESENTATION: A 35-year-old Sudanese woman, with a history of renal transplantation two and half years prior to presentation, was on a single immune suppre...

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Detalles Bibliográficos
Autores principales: Darwish, Ahmed, Nasr, Ayman O, El Hassan, Lamya A, Fahal, Ahmed H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928248/
https://www.ncbi.nlm.nih.gov/pubmed/20701786
http://dx.doi.org/10.1186/1752-1947-4-267
Descripción
Sumario:INTRODUCTION: Breast adenoma is common. However, in the setting of post-transplantation immune suppression it may be expressed differently. CASE PRESENTATION: A 35-year-old Sudanese woman, with a history of renal transplantation two and half years prior to presentation, was on a single immune suppression therapy in the form of cyclosporine-A since the transplantation. During a regular follow-up visit, she was noticed to have gingival hypertrophy and bilateral breast and axillary swellings. She underwent successful surgical resection of the bilateral fibroadenomas. CONCLUSIONS: Cyclosporine-A therapy post renal transplantation is associated with an increased incidence of benign breast changes as fibroadenoma. Regular follow-up and appropriate selection of immunosuppressant therapy are essential in the post transplantation management of these patients.