Linkage Specific Fucosylation of Alpha-1-Antitrypsin in Liver Cirrhosis and Cancer Patients: Implications for a Biomarker of Hepatocellular Carcinoma

BACKGROUND: We previously reported increased levels of protein-linked fucosylation with the development of liver cancer and identified many of the proteins containing the altered glycan structures. One such protein is alpha-1-antitrypsin (A1AT). To advance these studies, we performed N-linked glycan...

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Detalles Bibliográficos
Autores principales: Comunale, Mary Ann, Rodemich-Betesh, Lucy, Hafner, Julie, Wang, Mengjun, Norton, Pamela, Di Bisceglie, Adrian M., Block, Timothy, Mehta, Anand
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928295/
https://www.ncbi.nlm.nih.gov/pubmed/20811639
http://dx.doi.org/10.1371/journal.pone.0012419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928295/
https://www.ncbi.nlm.nih.gov/pubmed/20811639
http://dx.doi.org/10.1371/journal.pone.0012419

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