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Transcriptional Regulation of Human and Rat Hepatic Lipid Metabolism by the Grapefruit Flavonoid Naringenin: Role of PPARα, PPARγ and LXRα
Disruption of lipid and carbohydrate homeostasis is an important factor in the development of prevalent metabolic diseases such as diabetes, obesity, and atherosclerosis. Therefore, small molecules that could reduce insulin dependence and regulate dyslipidemia could have a dramatic effect on public...
Autores principales: | Goldwasser, Jonathan, Cohen, Pazit Y., Yang, Eric, Balaguer, Patrick, Yarmush, Martin L., Nahmias, Yaakov |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928300/ https://www.ncbi.nlm.nih.gov/pubmed/20811644 http://dx.doi.org/10.1371/journal.pone.0012399 |
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