Centrally Administered Pertussis Toxin Inhibits Microglia Migration to the Spinal Cord and Prevents Dissemination of Disease in an EAE Mouse Model

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) models are important vehicles for studying the effect of infectious elements such as Pertussis toxin (PTx) on disease processes related to acute demyelinating encephalomyelitis (ADEM) or multiple sclerosis (MS). PTx has pleotropic effects o...

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Detalles Bibliográficos
Autores principales: Yin, Jun-xiang, Tu, Jiang-long, Lin, Hao-jie, Shi, Fu-dong, Liu, Ru-lan, Zhao, Chong-bo, Coons, Stephen W., Kuniyoshi, Sandra, Shi, Jiong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928301/
https://www.ncbi.nlm.nih.gov/pubmed/20811645
http://dx.doi.org/10.1371/journal.pone.0012400

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