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Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes

OBJECTIVE: To analyze the cost-effectiveness of bariatric surgery in severely obese (BMI ≥35 kg/m(2)) adults who have diabetes, using a validated diabetes cost-effectiveness model. RESEARCH DESIGN AND METHODS: We expanded the Centers for Disease Control and Prevention–RTI Diabetes Cost-Effectiveness...

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Autores principales: Hoerger, Thomas J., Zhang, Ping, Segel, Joel E., Kahn, Henry S., Barker, Lawrence E., Couper, Steven
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928336/
https://www.ncbi.nlm.nih.gov/pubmed/20805271
http://dx.doi.org/10.2337/dc10-0554
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author Hoerger, Thomas J.
Zhang, Ping
Segel, Joel E.
Kahn, Henry S.
Barker, Lawrence E.
Couper, Steven
author_facet Hoerger, Thomas J.
Zhang, Ping
Segel, Joel E.
Kahn, Henry S.
Barker, Lawrence E.
Couper, Steven
author_sort Hoerger, Thomas J.
collection PubMed
description OBJECTIVE: To analyze the cost-effectiveness of bariatric surgery in severely obese (BMI ≥35 kg/m(2)) adults who have diabetes, using a validated diabetes cost-effectiveness model. RESEARCH DESIGN AND METHODS: We expanded the Centers for Disease Control and Prevention–RTI Diabetes Cost-Effectiveness Model to incorporate bariatric surgery. In this simulation model, bariatric surgery may lead to diabetes remission and reductions in other risk factors, which then lead to fewer diabetes complications and increased quality of life (QoL). Surgery is also associated with perioperative mortality and subsequent complications, and patients in remission may relapse to diabetes. We separately estimate the costs, quality-adjusted life-years (QALYs), and cost-effectiveness of gastric bypass surgery relative to usual diabetes care and of gastric banding surgery relative to usual diabetes care. We examine the cost-effectiveness of each type of surgery for severely obese individuals who are newly diagnosed with diabetes and for severely obese individuals with established diabetes. RESULTS: In all analyses, bariatric surgery increased QALYs and increased costs. Bypass surgery had cost-effectiveness ratios of $7,000/QALY and $12,000/QALY for severely obese patients with newly diagnosed and established diabetes, respectively. Banding surgery had cost-effectiveness ratios of $11,000/QALY and $13,000/QALY for the respective groups. In sensitivity analyses, the cost-effectiveness ratios were most affected by assumptions about the direct gain in QoL from BMI loss following surgery. CONCLUSIONS: Our analysis indicates that gastric bypass and gastric banding are cost-effective methods of reducing mortality and diabetes complications in severely obese adults with diabetes.
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spelling pubmed-29283362011-09-01 Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes Hoerger, Thomas J. Zhang, Ping Segel, Joel E. Kahn, Henry S. Barker, Lawrence E. Couper, Steven Diabetes Care Original Research OBJECTIVE: To analyze the cost-effectiveness of bariatric surgery in severely obese (BMI ≥35 kg/m(2)) adults who have diabetes, using a validated diabetes cost-effectiveness model. RESEARCH DESIGN AND METHODS: We expanded the Centers for Disease Control and Prevention–RTI Diabetes Cost-Effectiveness Model to incorporate bariatric surgery. In this simulation model, bariatric surgery may lead to diabetes remission and reductions in other risk factors, which then lead to fewer diabetes complications and increased quality of life (QoL). Surgery is also associated with perioperative mortality and subsequent complications, and patients in remission may relapse to diabetes. We separately estimate the costs, quality-adjusted life-years (QALYs), and cost-effectiveness of gastric bypass surgery relative to usual diabetes care and of gastric banding surgery relative to usual diabetes care. We examine the cost-effectiveness of each type of surgery for severely obese individuals who are newly diagnosed with diabetes and for severely obese individuals with established diabetes. RESULTS: In all analyses, bariatric surgery increased QALYs and increased costs. Bypass surgery had cost-effectiveness ratios of $7,000/QALY and $12,000/QALY for severely obese patients with newly diagnosed and established diabetes, respectively. Banding surgery had cost-effectiveness ratios of $11,000/QALY and $13,000/QALY for the respective groups. In sensitivity analyses, the cost-effectiveness ratios were most affected by assumptions about the direct gain in QoL from BMI loss following surgery. CONCLUSIONS: Our analysis indicates that gastric bypass and gastric banding are cost-effective methods of reducing mortality and diabetes complications in severely obese adults with diabetes. American Diabetes Association 2010-09 /pmc/articles/PMC2928336/ /pubmed/20805271 http://dx.doi.org/10.2337/dc10-0554 Text en © 2010 by the American Diabetes Association. https://creativecommons.org/licenses/by-nc-nd/3.0/Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ (https://creativecommons.org/licenses/by-nc-nd/3.0/) for details.
spellingShingle Original Research
Hoerger, Thomas J.
Zhang, Ping
Segel, Joel E.
Kahn, Henry S.
Barker, Lawrence E.
Couper, Steven
Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title_full Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title_fullStr Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title_full_unstemmed Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title_short Cost-Effectiveness of Bariatric Surgery for Severely Obese Adults With Diabetes
title_sort cost-effectiveness of bariatric surgery for severely obese adults with diabetes
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928336/
https://www.ncbi.nlm.nih.gov/pubmed/20805271
http://dx.doi.org/10.2337/dc10-0554
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