Saponins as cytotoxic agents: a review

Saponins are natural glycosides which possess a wide range of pharmacological properties including cytotoxic activity. In this review, the recent studies (2005–2009) concerning the cytotoxic activity of saponins have been summarized. The correlations between the structure and the cytotoxicity of bot...

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Detalles Bibliográficos
Autores principales: Podolak, Irma, Galanty, Agnieszka, Sobolewska, Danuta
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928447/
https://www.ncbi.nlm.nih.gov/pubmed/20835386
http://dx.doi.org/10.1007/s11101-010-9183-z
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author Podolak, Irma
Galanty, Agnieszka
Sobolewska, Danuta
author_facet Podolak, Irma
Galanty, Agnieszka
Sobolewska, Danuta
author_sort Podolak, Irma
collection PubMed
description Saponins are natural glycosides which possess a wide range of pharmacological properties including cytotoxic activity. In this review, the recent studies (2005–2009) concerning the cytotoxic activity of saponins have been summarized. The correlations between the structure and the cytotoxicity of both steroid and triterpenoid saponins have been described as well as the most common mechanisms of action.
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spelling pubmed-29284472010-09-10 Saponins as cytotoxic agents: a review Podolak, Irma Galanty, Agnieszka Sobolewska, Danuta Phytochem Rev Article Saponins are natural glycosides which possess a wide range of pharmacological properties including cytotoxic activity. In this review, the recent studies (2005–2009) concerning the cytotoxic activity of saponins have been summarized. The correlations between the structure and the cytotoxicity of both steroid and triterpenoid saponins have been described as well as the most common mechanisms of action. Springer Netherlands 2010-06-25 2010 /pmc/articles/PMC2928447/ /pubmed/20835386 http://dx.doi.org/10.1007/s11101-010-9183-z Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Podolak, Irma
Galanty, Agnieszka
Sobolewska, Danuta
Saponins as cytotoxic agents: a review
title Saponins as cytotoxic agents: a review
title_full Saponins as cytotoxic agents: a review
title_fullStr Saponins as cytotoxic agents: a review
title_full_unstemmed Saponins as cytotoxic agents: a review
title_short Saponins as cytotoxic agents: a review
title_sort saponins as cytotoxic agents: a review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928447/
https://www.ncbi.nlm.nih.gov/pubmed/20835386
http://dx.doi.org/10.1007/s11101-010-9183-z
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AT galantyagnieszka saponinsascytotoxicagentsareview
AT sobolewskadanuta saponinsascytotoxicagentsareview

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