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Epistasis: Obstacle or Advantage for Mapping Complex Traits?
Identification of genetic loci in complex traits has focused largely on one-dimensional genome scans to search for associations between single markers and the phenotype. There is mounting evidence that locus interactions, or epistasis, are a crucial component of the genetic architecture of biologica...
Autores principales: | Verhoeven, Koen J. F., Casella, George, McIntyre, Lauren M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928725/ https://www.ncbi.nlm.nih.gov/pubmed/20865037 http://dx.doi.org/10.1371/journal.pone.0012264 |
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