A Mechanistic View of the Role of E3 in Sumoylation

Sumoylation, the covalent attachment of SUMO (Small Ubiquitin-Like Modifier) to proteins, differs from other Ubl (Ubiquitin-like) pathways. In sumoylation, E2 ligase Ubc9 can function without E3 enzymes, albeit with lower reaction efficiency. Here, we study the mechanism through which E3 ligase RanB...

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Detalles Bibliográficos
Autores principales: Tozluoğlu, Melda, Karaca, Ezgi, Nussinov, Ruth, Haliloğlu, Türkan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928739/
https://www.ncbi.nlm.nih.gov/pubmed/20865051
http://dx.doi.org/10.1371/journal.pcbi.1000913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928739/
https://www.ncbi.nlm.nih.gov/pubmed/20865051
http://dx.doi.org/10.1371/journal.pcbi.1000913

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