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A Mechanistic View of the Role of E3 in Sumoylation
Sumoylation, the covalent attachment of SUMO (Small Ubiquitin-Like Modifier) to proteins, differs from other Ubl (Ubiquitin-like) pathways. In sumoylation, E2 ligase Ubc9 can function without E3 enzymes, albeit with lower reaction efficiency. Here, we study the mechanism through which E3 ligase RanB...
Autores principales: | Tozluoğlu, Melda, Karaca, Ezgi, Nussinov, Ruth, Haliloğlu, Türkan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928739/ https://www.ncbi.nlm.nih.gov/pubmed/20865051 http://dx.doi.org/10.1371/journal.pcbi.1000913 |
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