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Modeling and Dynamics of the Inward-Facing State of a Na(+)/Cl(−) Dependent Neurotransmitter Transporter Homologue

The leucine transporter (LeuT) has recently commanded exceptional attention due mainly to two distinctions; it provides the only crystal structures available for a protein homologous to the pharmacologically relevant neurotransmitter: sodium symporters (NSS), and, it exhibits a hallmark 5-TM inverte...

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Detalles Bibliográficos
Autores principales: Shaikh, Saher Afshan, Tajkhorshid, Emad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928745/
https://www.ncbi.nlm.nih.gov/pubmed/20865057
http://dx.doi.org/10.1371/journal.pcbi.1000905