Cargando…
Genetic Analysis of Baker's Yeast Msh4-Msh5 Reveals a Threshold Crossover Level for Meiotic Viability
During meiosis, the Msh4-Msh5 complex is thought to stabilize single-end invasion intermediates that form during early stages of recombination and subsequently bind to Holliday junctions to facilitate crossover formation. To analyze Msh4-Msh5 function, we mutagenized 57 residues in Saccharomyces cer...
Autores principales: | Nishant, K. T., Chen, Cheng, Shinohara, Miki, Shinohara, Akira, Alani, Eric |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928781/ https://www.ncbi.nlm.nih.gov/pubmed/20865162 http://dx.doi.org/10.1371/journal.pgen.1001083 |
Ejemplares similares
-
The Msh5 complex shows homeostatic localization in response to DNA double-strand breaks in yeast meiosis
por: Shinohara, Miki, et al.
Publicado: (2023) -
The pch2Δ Mutation in Baker's Yeast Alters Meiotic Crossover Levels and Confers a Defect in Crossover Interference
por: Zanders, Sarah, et al.
Publicado: (2009) -
MSH2 shapes the meiotic crossover landscape in relation to interhomolog polymorphism in Arabidopsis
por: Blackwell, Alexander R, et al.
Publicado: (2020) -
Genetic Analysis of mlh3 Mutations Reveals Interactions Between Crossover Promoting Factors During Meiosis in Baker’s Yeast
por: Brown, Megan Sonntag, et al.
Publicado: (2013) -
Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
por: Wiesendanger, Margrit, et al.
Publicado: (2000)