Mutations in the WTX - gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers

BACKGROUND: Genetically, colorectal cancers (CRCs) can be subdivided into tumors with chromosomal instability (CIN) or microsatellite instability (MSI). In both types of CRCs genes that are involved in the degradation of β-CATENIN are frequently mutated. Whereas in CIN CRCs APC (Adenomatous Polyposi...

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Detalles Bibliográficos
Autores principales: Scheel, Silvio K, Porzner, Marc, Pfeiffer, Sabine, Ormanns, Steffen, Kirchner, Thomas, Jung, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928794/
https://www.ncbi.nlm.nih.gov/pubmed/20696052
http://dx.doi.org/10.1186/1471-2407-10-413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928794/
https://www.ncbi.nlm.nih.gov/pubmed/20696052
http://dx.doi.org/10.1186/1471-2407-10-413

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