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Mutations in the WTX - gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers
BACKGROUND: Genetically, colorectal cancers (CRCs) can be subdivided into tumors with chromosomal instability (CIN) or microsatellite instability (MSI). In both types of CRCs genes that are involved in the degradation of β-CATENIN are frequently mutated. Whereas in CIN CRCs APC (Adenomatous Polyposi...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928794/ https://www.ncbi.nlm.nih.gov/pubmed/20696052 http://dx.doi.org/10.1186/1471-2407-10-413 |