A Ribosome-Associating Factor Chaperones Tail-Anchored Membrane Proteins

Hundreds of proteins are post-translationally inserted into the endoplasmic reticulum (ER) membrane by a single carboxy-terminal transmembrane domain (TMD)1. During targeting through the cytosol, the hydrophobic TMD of these tail-anchored (TA) proteins requires constant chaperoning to prevent aggreg...

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Detalles Bibliográficos
Autores principales: Mariappan, Malaiyalam, Li, Xingzhe, Stefanovic, Sandra, Sharma, Ajay, Mateja, Agnieszka, Keenan, Robert J., Hegde, Ramanujan S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928861/
https://www.ncbi.nlm.nih.gov/pubmed/20676083
http://dx.doi.org/10.1038/nature09296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928861/
https://www.ncbi.nlm.nih.gov/pubmed/20676083
http://dx.doi.org/10.1038/nature09296

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