Cargando…

A Ribosome-Associating Factor Chaperones Tail-Anchored Membrane Proteins

Hundreds of proteins are post-translationally inserted into the endoplasmic reticulum (ER) membrane by a single carboxy-terminal transmembrane domain (TMD)1. During targeting through the cytosol, the hydrophobic TMD of these tail-anchored (TA) proteins requires constant chaperoning to prevent aggreg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariappan, Malaiyalam, Li, Xingzhe, Stefanovic, Sandra, Sharma, Ajay, Mateja, Agnieszka, Keenan, Robert J., Hegde, Ramanujan S.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928861/ https://www.ncbi.nlm.nih.gov/pubmed/20676083 http://dx.doi.org/10.1038/nature09296

Ejemplares similares

Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins
por: Culver, Jacob A., et al.
Publicado: (2021)

Protein Targeting and Degradation are Coupled for Elimination of Mislocalized Proteins
por: Hessa, Tara, et al.
Publicado: (2011)

The Get1/2 insertase forms a channel to mediate the insertion of tail-anchored proteins into the ER
por: Heo, Paul, et al.
Publicado: (2023)

Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation
por: Itakura, Eisuke, et al.
Publicado: (2016)

Mechanism of signal-anchor triage during early steps of membrane protein insertion
por: Wu, Haoxi, et al.
Publicado: (2023)

A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis
por: Albanèse, Véronique, et al.
Publicado: (2010)

Mechanism of ribosome stalling during translation of a poly(A) tail
por: Chandrasekaran, Viswanathan, et al.
Publicado: (2019)

Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors
por: Zavodszky, Eszter, et al.
Publicado: (2019)

Nascent Chain Ubiquitination is Uncoupled from Degradation to Enable Protein Maturation
por: Li, Xia, et al.
Publicado: (2023)

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins
por: Stefanovic‐Barrett, Sandra, et al.
Publicado: (2018)

Substrate-driven assembly of a translocon for multipass membrane proteins
por: Sundaram, Arunkumar, et al.
Publicado: (2022)

Reconstitution of a Minimal Ribosome-Associated Ubiquitination Pathway with Purified Factors
por: Shao, Sichen, et al.
Publicado: (2014)

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane
por: Schuldiner, Maya, et al.
Publicado: (2008)

Distinct Requirements for Tail-Anchored Membrane Protein Biogenesis in Escherichia coli
por: Peschke, Markus, et al.
Publicado: (2019)

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast
por: Zhang, Ying, et al.
Publicado: (2021)

Structures of the scanning and engaged states of the mammalian SRP-ribosome complex
por: Voorhees, Rebecca M, et al.
Publicado: (2015)

Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation
por: Shao, Sichen, et al.
Publicado: (2013)

Chaperoning ribosome assembly
por: Karbstein, Katrin
Publicado: (2010)

Bacterial tail anchors can target to the mitochondrial outer membrane
por: Lutfullahoğlu-Bal, Güleycan, et al.
Publicado: (2017)

Signal sequences encode information for protein folding in the endoplasmic reticulum
por: Sun, Sha, et al.
Publicado: (2022)

Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination
por: Juszkiewicz, Szymon, et al.
Publicado: (2017)

The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane
por: Borgese, Nica, et al.
Publicado: (2003)

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes
por: Krumpe, Katrin, et al.
Publicado: (2012)

Multiple selection filters ensure accurate tail-anchored membrane protein targeting
por: Rao, Meera, et al.
Publicado: (2016)

Looking for a safe haven: tail-anchored proteins and their membrane insertion pathways
por: Mehlhorn, Dietmar G, et al.
Publicado: (2021)

New insights into the targeting of a subset of tail-anchored proteins to the outer mitochondrial membrane
por: Marty, Naomi J., et al.
Publicado: (2014)

Structure and Assembly Pathway of the Ribosome Quality Control Complex
por: Shao, Sichen, et al.
Publicado: (2015)

WRB and CAML Are Necessary and Sufficient to Mediate Tail-Anchored Protein Targeting to the ER Membrane
por: Vilardi, Fabio, et al.
Publicado: (2014)

Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2
por: Lin, Ku-Feng, et al.
Publicado: (2021)

Role of Hsp70 in Post-Translational Protein Targeting: Tail-Anchored Membrane Proteins and Beyond
por: Shan, Shu-ou
Publicado: (2023)

The Sec61 translocon limits IRE1α signaling during the unfolded protein response
por: Sundaram, Arunkumar, et al.
Publicado: (2017)

The ASC-1 Complex Disassembles Collided Ribosomes
por: Juszkiewicz, Szymon, et al.
Publicado: (2020)

ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway
por: Satpute-Krishnan, Prasanna, et al.
Publicado: (2014)

Ca(2+)-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane
por: Haßdenteufel, Sarah, et al.
Publicado: (2011)

Membrane-Specific Targeting of Tail-Anchored Proteins SECE1 and SECE2 Within Chloroplasts.
por: Anderson, Stacy A., et al.
Publicado: (2019)

Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion
por: Chio, Un Seng, et al.
Publicado: (2021)

A functional link between the co-translational protein translocation pathway and the UPR
por: Plumb, Rachel, et al.
Publicado: (2015)

A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
por: Drwesh, Layla, et al.
Publicado: (2022)

The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon
por: von der Malsburg, Karina, et al.
Publicado: (2015)

The Association of BAG6 with SGTA and Tail-Anchored Proteins
por: Leznicki, Pawel, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_s1s850shm4l864p4ppla84ulb7