Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

We found that rat central auditory neurons fire action potentials in a precise sequence of mini-bursts prior to hearing onset. This stereotyped pattern is initiated by hair cells within the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca(2+) spik...

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Detalles Bibliográficos
Autores principales: Tritsch, Nicolas X., Rodríguez-Contreras, Adrián, Crins, Tom T.H., Wang, Han Chin, Borst, J. Gerard G., Bergles, Dwight E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928883/
https://www.ncbi.nlm.nih.gov/pubmed/20676105
http://dx.doi.org/10.1038/nn.2604
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author Tritsch, Nicolas X.
Rodríguez-Contreras, Adrián
Crins, Tom T.H.
Wang, Han Chin
Borst, J. Gerard G.
Bergles, Dwight E.
author_facet Tritsch, Nicolas X.
Rodríguez-Contreras, Adrián
Crins, Tom T.H.
Wang, Han Chin
Borst, J. Gerard G.
Bergles, Dwight E.
author_sort Tritsch, Nicolas X.
collection PubMed
description We found that rat central auditory neurons fire action potentials in a precise sequence of mini-bursts prior to hearing onset. This stereotyped pattern is initiated by hair cells within the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca(2+) spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses.
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spelling pubmed-29288832011-03-01 Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset Tritsch, Nicolas X. Rodríguez-Contreras, Adrián Crins, Tom T.H. Wang, Han Chin Borst, J. Gerard G. Bergles, Dwight E. Nat Neurosci Article We found that rat central auditory neurons fire action potentials in a precise sequence of mini-bursts prior to hearing onset. This stereotyped pattern is initiated by hair cells within the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca(2+) spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses. 2010-08-01 2010-09 /pmc/articles/PMC2928883/ /pubmed/20676105 http://dx.doi.org/10.1038/nn.2604 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Tritsch, Nicolas X.
Rodríguez-Contreras, Adrián
Crins, Tom T.H.
Wang, Han Chin
Borst, J. Gerard G.
Bergles, Dwight E.
Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title_full Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title_fullStr Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title_full_unstemmed Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title_short Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
title_sort calcium action potentials in hair cells pattern auditory neuron activity before hearing onset
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928883/
https://www.ncbi.nlm.nih.gov/pubmed/20676105
http://dx.doi.org/10.1038/nn.2604
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