In Vitro Transformation of Primary Human CD34+ Cells by AML Fusion Oncogenes: Early Gene Expression Profiling Reveals Possible Drug Target in AML

Different fusion oncogenes in acute myeloid leukemia (AML) have distinct clinical and laboratory features suggesting different modes of malignant transformation. Here we compare the in vitro effects of representatives of 4 major groups of AML fusion oncogenes on primary human CD34+ cells. As expecte...

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Detalles Bibliográficos
Autores principales: Abdul-Nabi, Anmaar M., Yassin, Enas R., Varghese, Nobish, Deshmukh, Hrishikesh, Yaseen, Nabeel R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929205/
https://www.ncbi.nlm.nih.gov/pubmed/20805992
http://dx.doi.org/10.1371/journal.pone.0012464

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