PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis

OBJECTIVE: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. METHODS: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria w...

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Detalles Bibliográficos
Autores principales: Tauzin, Marcie, Rabalais, Amy, Hagan, Joseph L, Wood, Charles G, Ferris, Robert L, Walvekar, Rohan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929233/
https://www.ncbi.nlm.nih.gov/pubmed/20712875
http://dx.doi.org/10.1186/1477-7819-8-70
Descripción
Sumario:OBJECTIVE: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. METHODS: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria were further analyzed. RESULTS: The frequency of RPLN was 20.8% (11/53). Advanced T stage cancer (OR = 5.6250, 95% CI: 1.06 - 29.80, p = 0.0410) and advanced clinical N stage cancer (i.e. N2+) had higher odds (OR = 3.9773, 95% CI: 0.9628 - 16.4291) of being RPLN positive as compared to N0-1 patients. CONCLUSIONS: Pre-treatment PET-CT can be used as a staging tool to aid in treatment planning of OPSCC, as rates of RPLN and nodal metastasis are consistent with those reported in the literature. Advanced T and N stage are associated with a greater odds ratio of being RPLN positive by PET-CT imaging.

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