PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis

OBJECTIVE: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. METHODS: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria w...

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Autores principales: Tauzin, Marcie, Rabalais, Amy, Hagan, Joseph L, Wood, Charles G, Ferris, Robert L, Walvekar, Rohan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929233/
https://www.ncbi.nlm.nih.gov/pubmed/20712875
http://dx.doi.org/10.1186/1477-7819-8-70
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author Tauzin, Marcie
Rabalais, Amy
Hagan, Joseph L
Wood, Charles G
Ferris, Robert L
Walvekar, Rohan R
author_facet Tauzin, Marcie
Rabalais, Amy
Hagan, Joseph L
Wood, Charles G
Ferris, Robert L
Walvekar, Rohan R
author_sort Tauzin, Marcie
collection PubMed
description OBJECTIVE: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. METHODS: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria were further analyzed. RESULTS: The frequency of RPLN was 20.8% (11/53). Advanced T stage cancer (OR = 5.6250, 95% CI: 1.06 - 29.80, p = 0.0410) and advanced clinical N stage cancer (i.e. N2+) had higher odds (OR = 3.9773, 95% CI: 0.9628 - 16.4291) of being RPLN positive as compared to N0-1 patients. CONCLUSIONS: Pre-treatment PET-CT can be used as a staging tool to aid in treatment planning of OPSCC, as rates of RPLN and nodal metastasis are consistent with those reported in the literature. Advanced T and N stage are associated with a greater odds ratio of being RPLN positive by PET-CT imaging.
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spelling pubmed-29292332010-08-28 PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis Tauzin, Marcie Rabalais, Amy Hagan, Joseph L Wood, Charles G Ferris, Robert L Walvekar, Rohan R World J Surg Oncol Research OBJECTIVE: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. METHODS: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria were further analyzed. RESULTS: The frequency of RPLN was 20.8% (11/53). Advanced T stage cancer (OR = 5.6250, 95% CI: 1.06 - 29.80, p = 0.0410) and advanced clinical N stage cancer (i.e. N2+) had higher odds (OR = 3.9773, 95% CI: 0.9628 - 16.4291) of being RPLN positive as compared to N0-1 patients. CONCLUSIONS: Pre-treatment PET-CT can be used as a staging tool to aid in treatment planning of OPSCC, as rates of RPLN and nodal metastasis are consistent with those reported in the literature. Advanced T and N stage are associated with a greater odds ratio of being RPLN positive by PET-CT imaging. BioMed Central 2010-08-16 /pmc/articles/PMC2929233/ /pubmed/20712875 http://dx.doi.org/10.1186/1477-7819-8-70 Text en Copyright ©2010 Tauzin et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Tauzin, Marcie
Rabalais, Amy
Hagan, Joseph L
Wood, Charles G
Ferris, Robert L
Walvekar, Rohan R
PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title_full PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title_fullStr PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title_full_unstemmed PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title_short PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
title_sort pet-ct staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929233/
https://www.ncbi.nlm.nih.gov/pubmed/20712875
http://dx.doi.org/10.1186/1477-7819-8-70
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