Cargando…

Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

Myc is activated in many tumours, yet, paradoxically, stimulates differentiation in mammalian epidermis. To test whether the epidermis responds differently to different levels of Myc, we treated K14MycER transgenic mice with a range of concentrations of the inducing agent, 4-hydroxy-tamoxifen (4OHT)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Berta, Melanie A, Baker, Christopher M, Cottle, Denny L, Watt, Fiona M
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929372/ https://www.ncbi.nlm.nih.gov/pubmed/20043278 http://dx.doi.org/10.1002/emmm.200900047

Ejemplares similares

The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
por: Kretzschmar, Kai, et al.
Publicado: (2015)

Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation
por: Frye, Michaela, et al.
Publicado: (2007)

c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
por: Cottle, Denny L., et al.
Publicado: (2013)

Myc-dependent dedifferentiation of Gata6(+) epidermal cells resembles reversal of terminal differentiation
por: Bernabé-Rubio, Miguel, et al.
Publicado: (2023)

Epidermal stem cell diversity and quiescence
por: Watt, Fiona M, et al.
Publicado: (2009)

Human epidermal stem cell differentiation is modulated by specific lipid subspecies
por: Vietri Rudan, Matteo, et al.
Publicado: (2020)

Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
por: Baker, Christopher M., et al.
Publicado: (2010)

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate
por: Blanco, Sandra, et al.
Publicado: (2011)

BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
por: Kretzschmar, Kai, et al.
Publicado: (2014)

Epidermal Notch signalling: differentiation, cancer and adhesion
por: Watt, Fiona M, et al.
Publicado: (2008)

Understanding Human Epidermal Stem Cells at Single-Cell Resolution
por: Negri, Victor Augusti, et al.
Publicado: (2022)

Micro-scaled topographies direct differentiation of human epidermal stem cells
por: Zijl, Sebastiaan, et al.
Publicado: (2019)

Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation
por: Connelly, John T., et al.
Publicado: (2011)

Epidermal stem cells are retained in vivo throughout skin aging
por: Giangreco, Adam, et al.
Publicado: (2008)

Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels
por: Schuhmacher, Marino, et al.
Publicado: (2013)

Luteolin-7-glucoside Promotes Human Epidermal Stem Cell Proliferation by Upregulating β-Catenin, c-Myc, and Cyclin Expression
por: Wan, Dapeng, et al.
Publicado: (2019)

Epidermal stem cells participate in the repair of scalds via Nanog and Myc regulation
por: Yin, Delong, et al.
Publicado: (2022)

A reductionist approach to determine the effect of cell-cell contact on human epidermal stem cell differentiation
por: Louis, Blaise, et al.
Publicado: (2022)

AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging
por: Zhou, Jing, et al.
Publicado: (2020)

p53 activity contributes to defective interfollicular epidermal differentiation in hyperproliferative murine skin
por: Cottle, D.L., et al.
Publicado: (2015)

Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma()
por: Szemes, Marianna, et al.
Publicado: (2018)

Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC
por: Li, Hongzhen, et al.
Publicado: (2020)

Dose-Dependent Effects of Melatonin on the Viability, Proliferation, and Differentiation of Dental Pulp Stem Cells (DPSCs)
por: Patil, Shankargouda, et al.
Publicado: (2022)

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
por: Gebhardt, Anneli, et al.
Publicado: (2006)

S146L in MYC is a context-dependent activating substitution in cancer development
por: Hinds, John W., et al.
Publicado: (2022)

A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation
por: Castell, Alina, et al.
Publicado: (2018)

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
por: Kretzschmar, Kai, et al.
Publicado: (2016)

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner
por: Xia, Pengyan, et al.
Publicado: (2014)

Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness
por: Mobasseri, Seyedeh Atefeh, et al.
Publicado: (2019)

Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
por: Nilsson, Lisa M., et al.
Publicado: (2012)

Context-dependent transcriptional regulations of YAP/TAZ in stem cell and differentiation
por: Luo, Juan, et al.
Publicado: (2022)

Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
por: Testini, Chiara, et al.
Publicado: (2019)

Hyperoxia Inhibits Proliferation of Retinal Endothelial Cells in a Myc-Dependent Manner
por: Singh, Charandeep, et al.
Publicado: (2021)

c-Myc-Induced Survivin Is Essential for Promoting the Notch-Dependent T Cell Differentiation from Hematopoietic Stem Cells
por: Haque, Rizwanul, et al.
Publicado: (2017)

Ras in epidermal proliferation
por: Drosten, Matthias, et al.
Publicado: (2014)

Hair follicle epidermal stem cells define a niche for tactile sensation
por: Cheng, Chun-Chun, et al.
Publicado: (2018)

Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells
por: Ghahramani, Arsham, et al.
Publicado: (2018)

Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
por: Lichtenberger, Beate M., et al.
Publicado: (2016)

Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture
por: Negri, Victor A., et al.
Publicado: (2019)

Stomatal development in the context of epidermal tissues
por: Torii, Keiko U
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jhhqai082nouiaou1sfmjoscl2