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Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution
Gastric outlet obstruction (GOO) after esophagectomy is a morbid outcome and significantly hinders quality of life for end-stage esophageal cancer patients. In the pre-stent era, palliation consisted of chemotherapy, radiation, tumor ablation, or stricture dilation. In the current era, palliative st...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929413/ https://www.ncbi.nlm.nih.gov/pubmed/20805942 http://dx.doi.org/10.1159/000315560 |
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author | Rueth, Natasha M. Andrade, Rafael S. Groth, Shawn S. Maddaus, Michael A. D’Cunha, Jonathan |
author_facet | Rueth, Natasha M. Andrade, Rafael S. Groth, Shawn S. Maddaus, Michael A. D’Cunha, Jonathan |
author_sort | Rueth, Natasha M. |
collection | PubMed |
description | Gastric outlet obstruction (GOO) after esophagectomy is a morbid outcome and significantly hinders quality of life for end-stage esophageal cancer patients. In the pre-stent era, palliation consisted of chemotherapy, radiation, tumor ablation, or stricture dilation. In the current era, palliative stenting has emerged as an additional tool; however, migration and tumor ingrowth are ongoing challenges. To mitigate these challenges, we developed a novel, hybrid, stent-based approach for the palliative management of GOO. We present a patient with esophageal cancer diagnosed with recurrent, metastatic disease 1 year after esophagectomy. She developed dehydration and intractable emesis, which significantly interfered with her quality of life. For palliation, we dilated the stenosis and proceeded with our stent-based solution. Using a combined endoscopic and fluoroscopic approach, we placed a 12-mm silicone salivary bypass tube across the pylorus, where it kinked slightly because of local tumor biology. To bridge this defect and ensure luminal patency, we placed a nitinol tracheobronchial stent through the silicone stent. Clinically, the patient had immediate relief from her pre-operative symptoms and was discharged home on a liquid diet. In conclusion, GOO and malignant dysphagia after esophagectomy are significant challenges for patients with end-stage disease. Palliative stenting is a viable option, but migration and tumor ingrowth are common complications. The hybrid approach presented here provides a unique solution to these potential pitfalls. The flared silicone tube minimized the chance of migration and impaired tumor ingrowth. The nitinol stent aided with patency and overcame the challenges of the soft tube. This novel strategy achieved palliation, describing another endoscopic option in the treatment of malignant GOO. |
format | Text |
id | pubmed-2929413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-29294132010-08-30 Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution Rueth, Natasha M. Andrade, Rafael S. Groth, Shawn S. Maddaus, Michael A. D’Cunha, Jonathan Case Rep Gastroenterol Published: June 2010 Gastric outlet obstruction (GOO) after esophagectomy is a morbid outcome and significantly hinders quality of life for end-stage esophageal cancer patients. In the pre-stent era, palliation consisted of chemotherapy, radiation, tumor ablation, or stricture dilation. In the current era, palliative stenting has emerged as an additional tool; however, migration and tumor ingrowth are ongoing challenges. To mitigate these challenges, we developed a novel, hybrid, stent-based approach for the palliative management of GOO. We present a patient with esophageal cancer diagnosed with recurrent, metastatic disease 1 year after esophagectomy. She developed dehydration and intractable emesis, which significantly interfered with her quality of life. For palliation, we dilated the stenosis and proceeded with our stent-based solution. Using a combined endoscopic and fluoroscopic approach, we placed a 12-mm silicone salivary bypass tube across the pylorus, where it kinked slightly because of local tumor biology. To bridge this defect and ensure luminal patency, we placed a nitinol tracheobronchial stent through the silicone stent. Clinically, the patient had immediate relief from her pre-operative symptoms and was discharged home on a liquid diet. In conclusion, GOO and malignant dysphagia after esophagectomy are significant challenges for patients with end-stage disease. Palliative stenting is a viable option, but migration and tumor ingrowth are common complications. The hybrid approach presented here provides a unique solution to these potential pitfalls. The flared silicone tube minimized the chance of migration and impaired tumor ingrowth. The nitinol stent aided with patency and overcame the challenges of the soft tube. This novel strategy achieved palliation, describing another endoscopic option in the treatment of malignant GOO. S. Karger AG 2010-06-11 /pmc/articles/PMC2929413/ /pubmed/20805942 http://dx.doi.org/10.1159/000315560 Text en Copyright © 2010 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: June 2010 Rueth, Natasha M. Andrade, Rafael S. Groth, Shawn S. Maddaus, Michael A. D’Cunha, Jonathan Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title | Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title_full | Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title_fullStr | Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title_full_unstemmed | Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title_short | Gastric Outlet Obstruction Palliation: A Novel Stent-Based Solution |
title_sort | gastric outlet obstruction palliation: a novel stent-based solution |
topic | Published: June 2010 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929413/ https://www.ncbi.nlm.nih.gov/pubmed/20805942 http://dx.doi.org/10.1159/000315560 |
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