Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?

Genes involved in alcoholism have consensus sites for the transcription factor activator protein (TFAP) 2β. In the present study, we investigated TFAP-2β protein levels in the ethanol-preferring alko, alcohol (AA) and the ethanol-avoiding alko, non-alcohol (ANA) rat lines. Furthermore, basal and eth...

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Detalles Bibliográficos
Autores principales: Oreland, S., Daoura, L., Gustafsson-Ericson, L., Damberg, M., Hyytiä, P., Oreland, L., Nylander, Ingrid
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Basic Neurosciences, Genetics and Immunology - Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929433/
https://www.ncbi.nlm.nih.gov/pubmed/20690033
http://dx.doi.org/10.1007/s00702-010-0448-x
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author Oreland, S.
Daoura, L.
Gustafsson-Ericson, L.
Damberg, M.
Hyytiä, P.
Oreland, L.
Nylander, Ingrid
author_facet Oreland, S.
Daoura, L.
Gustafsson-Ericson, L.
Damberg, M.
Hyytiä, P.
Oreland, L.
Nylander, Ingrid
author_sort Oreland, S.
collection PubMed
description Genes involved in alcoholism have consensus sites for the transcription factor activator protein (TFAP) 2β. In the present study, we investigated TFAP-2β protein levels in the ethanol-preferring alko, alcohol (AA) and the ethanol-avoiding alko, non-alcohol (ANA) rat lines. Furthermore, basal and ethanol-induced TFAP-2β levels were examined in Wistar rats exposed to different early postnatal environments that are known to affect later ethanol consumption. Taken together, we found differences in brainstem TFAP-2β protein between the AA and ANA rats.
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spelling pubmed-29294332010-09-10 Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption? Oreland, S. Daoura, L. Gustafsson-Ericson, L. Damberg, M. Hyytiä, P. Oreland, L. Nylander, Ingrid J Neural Transm (Vienna) Basic Neurosciences, Genetics and Immunology - Short Communication Genes involved in alcoholism have consensus sites for the transcription factor activator protein (TFAP) 2β. In the present study, we investigated TFAP-2β protein levels in the ethanol-preferring alko, alcohol (AA) and the ethanol-avoiding alko, non-alcohol (ANA) rat lines. Furthermore, basal and ethanol-induced TFAP-2β levels were examined in Wistar rats exposed to different early postnatal environments that are known to affect later ethanol consumption. Taken together, we found differences in brainstem TFAP-2β protein between the AA and ANA rats. Springer Vienna 2010-08-06 2010 /pmc/articles/PMC2929433/ /pubmed/20690033 http://dx.doi.org/10.1007/s00702-010-0448-x Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Basic Neurosciences, Genetics and Immunology - Short Communication
Oreland, S.
Daoura, L.
Gustafsson-Ericson, L.
Damberg, M.
Hyytiä, P.
Oreland, L.
Nylander, Ingrid
Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title_full Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title_fullStr Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title_full_unstemmed Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title_short Does the transcription factor AP-2β have an impact on the genetic and early environmental influence on ethanol consumption?
title_sort does the transcription factor ap-2β have an impact on the genetic and early environmental influence on ethanol consumption?
topic Basic Neurosciences, Genetics and Immunology - Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929433/
https://www.ncbi.nlm.nih.gov/pubmed/20690033
http://dx.doi.org/10.1007/s00702-010-0448-x
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