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Enhanced Gene Delivery Mediated by Low Molecular Weight Chitosan/DNA Complexes: Effect of pH and Serum
This study was designed to systematically evaluate the influence of pH and serum on the transfection process of chitosan–DNA complexes, with the objective of maximizing their efficiency. The hydrodynamic diameter of the complexes, measured by dynamic light scattering (DLS), was found to increase wit...
Autores principales: | Nimesh, Surendra, Thibault, Marc M., Lavertu, Marc, Buschmann, Michael D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929434/ https://www.ncbi.nlm.nih.gov/pubmed/20454872 http://dx.doi.org/10.1007/s12033-010-9286-1 |
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