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Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor
Several lines of evidence point to a role for non-coding RNA in transcriptional repression by Polycomb group (PcG) proteins but the precise mechanism remains unclear. Here we show that MOV10, a putative RNA helicase previously implicated in post-transcriptional gene silencing, co-purifies and intera...
Autores principales: | El Messaoudi-Aubert, Selma, Nicholls, James, Maertens, Goedele N., Brookes, Sharon, Bernstein, Emily, Peters, Gordon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929459/ https://www.ncbi.nlm.nih.gov/pubmed/20543829 http://dx.doi.org/10.1038/nsmb.1824 |
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