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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy

Double-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. C...

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Detalles Bibliográficos
Autores principales:	Podhorecka, Monika, Skladanowski, Andrzej, Bozko, Przemyslaw
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2010
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929501/ https://www.ncbi.nlm.nih.gov/pubmed/20811597 http://dx.doi.org/10.4061/2010/920161

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