Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form

A colorimetric method for the analysis of escitalopram oxalate in pure form and in tablets has been developed based on the formation of chloroform soluble ion associates with bromocresol green acidic dye. The extract of ion associates exhibited absorption maxima at 417 nm obeying Beer's law in...

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Detalles Bibliográficos
Autores principales: Vetrichelvan, T., Arul, K., Sumithra, M., Umadevi, B.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929796/
https://www.ncbi.nlm.nih.gov/pubmed/20838541
http://dx.doi.org/10.4103/0250-474X.65011
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author Vetrichelvan, T.
Arul, K.
Sumithra, M.
Umadevi, B.
author_facet Vetrichelvan, T.
Arul, K.
Sumithra, M.
Umadevi, B.
author_sort Vetrichelvan, T.
collection PubMed
description A colorimetric method for the analysis of escitalopram oxalate in pure form and in tablets has been developed based on the formation of chloroform soluble ion associates with bromocresol green acidic dye. The extract of ion associates exhibited absorption maxima at 417 nm obeying Beer's law in the range of 2-10 µg/ml. The method is simple, precise and accurate with recovery of 98-102% and does not require any separation of soluble excipients from tablet dosage form.
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spelling pubmed-29297962010-09-13 Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form Vetrichelvan, T. Arul, K. Sumithra, M. Umadevi, B. Indian J Pharm Sci Short Communications A colorimetric method for the analysis of escitalopram oxalate in pure form and in tablets has been developed based on the formation of chloroform soluble ion associates with bromocresol green acidic dye. The extract of ion associates exhibited absorption maxima at 417 nm obeying Beer's law in the range of 2-10 µg/ml. The method is simple, precise and accurate with recovery of 98-102% and does not require any separation of soluble excipients from tablet dosage form. Medknow Publications 2010 /pmc/articles/PMC2929796/ /pubmed/20838541 http://dx.doi.org/10.4103/0250-474X.65011 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communications
Vetrichelvan, T.
Arul, K.
Sumithra, M.
Umadevi, B.
Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title_full Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title_fullStr Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title_full_unstemmed Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title_short Colorimetric Method for the Estimation of Escitalopram Oxalate in Tablet Dosage Form
title_sort colorimetric method for the estimation of escitalopram oxalate in tablet dosage form
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929796/
https://www.ncbi.nlm.nih.gov/pubmed/20838541
http://dx.doi.org/10.4103/0250-474X.65011
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AT arulk colorimetricmethodfortheestimationofescitalopramoxalateintabletdosageform
AT sumithram colorimetricmethodfortheestimationofescitalopramoxalateintabletdosageform
AT umadevib colorimetricmethodfortheestimationofescitalopramoxalateintabletdosageform

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