Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens

PURPOSE: To determine if there is increased mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) damage with age in the lenses of rats. We also explored the immunolocalization of 8-oxoguanine DNA glycosylase 1 (OGG1) and AP endonuclease 1 (APE1) in the lens and studied three of the predominant base exci...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, Lu, Zhang, Lan, Bai, Jie, Ge, HongYan, Liu, Ping
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929939/
https://www.ncbi.nlm.nih.gov/pubmed/20808729

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