Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome

The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either compound features (i.e., QSAR), in vitro cell based assays or molecular profiling of target tissues...

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Detalles Bibliográficos
Autores principales: Antczak, Philipp, Ortega, Fernando, Chipman, J. Kevin, Falciani, Francesco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929951/
https://www.ncbi.nlm.nih.gov/pubmed/20811577
http://dx.doi.org/10.1371/journal.pone.0012385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929951/
https://www.ncbi.nlm.nih.gov/pubmed/20811577
http://dx.doi.org/10.1371/journal.pone.0012385

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