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In Macrophages, Caspase-1 Activation by SopE and the Type III Secretion System-1 of S. Typhimurium Can Proceed in the Absence of Flagellin

The innate immune system is of vital importance for protection against infectious pathogens. Inflammasome mediated caspase-1 activation and subsequent release of pro-inflammatory cytokines like IL-1β and IL-18 is an important arm of the innate immune system. Salmonella enterica subspecies 1 serovar...

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Detalles Bibliográficos
Autores principales:	Hoffmann, Claudia, Galle, Marlies, Dilling, Sabrina, Käppeli, Rina, Müller, Andreas J., Songhet, Pascal, Beyaert, Rudi, Hardt, Wolf-Dietrich
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930008/ https://www.ncbi.nlm.nih.gov/pubmed/20814576 http://dx.doi.org/10.1371/journal.pone.0012477

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