In vivo evidence for the fibrillar structures of Sup35 prions in yeast cells

Yeast prion [PSI(+)] is caused by aggregated structures of the Sup35 protein. Although Sup35 forms typical amyloid fibrils in vitro, there is no direct evidence for the fibrillar structures of Sup35 in vivo. We analyzed [PSI(+)] cells in which Sup35 fused with green fluorescent protein (GFP) formed...

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Detalles Bibliográficos
Autores principales: Kawai-Noma, Shigeko, Pack, Chan-Gi, Kojidani, Tomoko, Asakawa, Haruhiko, Hiraoka, Yasushi, Kinjo, Masataka, Haraguchi, Tokuko, Taguchi, Hideki, Hirata, Aiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930275/
https://www.ncbi.nlm.nih.gov/pubmed/20643880
http://dx.doi.org/10.1083/jcb.201002149

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