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VASP: A Volumetric Analysis of Surface Properties Yields Insights into Protein-Ligand Binding Specificity

Many algorithms that compare protein structures can reveal similarities that suggest related biological functions, even at great evolutionary distances. Proteins with related function often exhibit differences in binding specificity, but few algorithms identify structural variations that effect spec...

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Detalles Bibliográficos
Autores principales: Chen, Brian Y., Honig, Barry
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930297/
https://www.ncbi.nlm.nih.gov/pubmed/20814581
http://dx.doi.org/10.1371/journal.pcbi.1000881