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VASP: A Volumetric Analysis of Surface Properties Yields Insights into Protein-Ligand Binding Specificity
Many algorithms that compare protein structures can reveal similarities that suggest related biological functions, even at great evolutionary distances. Proteins with related function often exhibit differences in binding specificity, but few algorithms identify structural variations that effect spec...
Autores principales: | Chen, Brian Y., Honig, Barry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930297/ https://www.ncbi.nlm.nih.gov/pubmed/20814581 http://dx.doi.org/10.1371/journal.pcbi.1000881 |
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