EMMPRIN Promotes Melanoma Cells Malignant Properties through a HIF-2alpha Mediated Up-Regulation of VEGF-Receptor-2

EMMPRIN's expression in melanoma tissue was reported to be predictive of poor prognosis. Here we demonstrate that EMMPRIN up-regulated VEGF receptor-2 (VEGFR-2) in two different primary melanoma cell lines and consequently increased migration and proliferation of these cells while inhibiting th...

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Detalles Bibliográficos
Autores principales: Bougatef, Faten, Menashi, Suzanne, Khayati, Farah, Naïmi, Benyoussef, Porcher, Raphaël, Podgorniak, Marie-Pierre, Millot, Guy, Janin, Anne, Calvo, Fabien, Lebbé, Céleste, Mourah, Samia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930842/
https://www.ncbi.nlm.nih.gov/pubmed/20824203
http://dx.doi.org/10.1371/journal.pone.0012265

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