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Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas

BACKGROUND: In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist kill...

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Detalles Bibliográficos
Autores principales: Mehra, Smriti, Pahar, Bapi, Dutta, Noton K., Conerly, Cecily N., Philippi-Falkenstein, Kathrine, Alvarez, Xavier, Kaushal, Deepak
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930844/
https://www.ncbi.nlm.nih.gov/pubmed/20824205
http://dx.doi.org/10.1371/journal.pone.0012266

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