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Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas
BACKGROUND: In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist kill...
Autores principales: | Mehra, Smriti, Pahar, Bapi, Dutta, Noton K., Conerly, Cecily N., Philippi-Falkenstein, Kathrine, Alvarez, Xavier, Kaushal, Deepak |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930844/ https://www.ncbi.nlm.nih.gov/pubmed/20824205 http://dx.doi.org/10.1371/journal.pone.0012266 |
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